London’s vibrant office market is undergoing a sweeping reinvention. In the short term, the ongoing evolution of the pandemic and, to a lesser extent, remaining UK-EU negotiations represent risks to the post-COVID, post-Brexit recovery, with considerable variance in possible outcomes. Over the long term, London’s office market will be shaped by global macro trends, namely: public health and safety; environmental, social, and governance (ESG) requirements; demographics; and technology. The combined effect of these forces, and the two simultaneous, once-in-a-century events, will be to reinvent the London office market in ways big and small.